Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

Diseases and toxins may lead to death of active liver tissue, resulting in a loss of total clearance capacity at the whole-body level. However, it remains difficult to study, whether the loss of metabolizing tissue is sufficient to explain loss of metabolic capacity of the liver or whether the survi...

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Detalles Bibliográficos
Autores principales: Schenk, Arne, Ghallab, Ahmed, Hofmann, Ute, Hassan, Reham, Schwarz, Michael, Schuppert, Andreas, Schwen, Lars Ole, Braeuning, Albert, Teutonico, Donato, Hengstler, Jan G., Kuepfer, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524914/
https://www.ncbi.nlm.nih.gov/pubmed/28740200
http://dx.doi.org/10.1038/s41598-017-04574-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524914/
https://www.ncbi.nlm.nih.gov/pubmed/28740200
http://dx.doi.org/10.1038/s41598-017-04574-z

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