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Depression and Catechol-O-methyltransferase (COMT) genetic variants are associated with pain in Parkinson’s disease

Pain is a distressing symptom of Parkinson disease (PD). We aim to determine whether the genetic variants of chronic pain-related genes contribute to pain in PD patients. We included 418 PD patients and evaluated pain severity on King’s PD pain scale. We genotyped rs6267, rs6269, rs4633, rs4818 and...

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Detalles Bibliográficos
Autores principales:	Lin, Chin-Hsien, Chaudhuri, K. Ray, Fan, Jun-Yu, Ko, Chia-I., Rizos, Alexandra, Chang, Chia-Wen, Lin, Han-I., Wu, Yih-Ru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524945/ https://www.ncbi.nlm.nih.gov/pubmed/28740224 http://dx.doi.org/10.1038/s41598-017-06782-z

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