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Depression and Catechol-O-methyltransferase (COMT) genetic variants are associated with pain in Parkinson’s disease
Pain is a distressing symptom of Parkinson disease (PD). We aim to determine whether the genetic variants of chronic pain-related genes contribute to pain in PD patients. We included 418 PD patients and evaluated pain severity on King’s PD pain scale. We genotyped rs6267, rs6269, rs4633, rs4818 and...
Autores principales: | Lin, Chin-Hsien, Chaudhuri, K. Ray, Fan, Jun-Yu, Ko, Chia-I., Rizos, Alexandra, Chang, Chia-Wen, Lin, Han-I., Wu, Yih-Ru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524945/ https://www.ncbi.nlm.nih.gov/pubmed/28740224 http://dx.doi.org/10.1038/s41598-017-06782-z |
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