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Quantitative analysis of 3D alignment quality: its impact on soft-validation, particle pruning and homogeneity analysis
Single Particle Analysis using cryo-electron microscopy is a structural biology technique aimed at capturing the three-dimensional (3D) conformation of biological macromolecules. Projection images used to construct the 3D density map are characterized by a very low signal-to-noise ratio to minimize...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524947/ https://www.ncbi.nlm.nih.gov/pubmed/28740215 http://dx.doi.org/10.1038/s41598-017-06526-z |