miR-155 effectively induces apoptosis in K562 Philadelphia positive cell line through upregulation of p27kip1

[Image: see text] Introduction: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder caused by the Philadelphia chromosome translocation, at (9; 22), which results in BCR-ABL fusion tyrosine kinase oncoprotein. This fusion induces down-regulation of miR-155. Upregulation of miR-155 ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Edalati Fathabad, Mahdi, Karimipoor, Morteza, Alizadeh, Shaban, Abdoli, Asghar, Atashi, Amir, Sayadi, Mahtab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524985/
https://www.ncbi.nlm.nih.gov/pubmed/28752075
http://dx.doi.org/10.15171/bi.2017.14

Ejemplares similares

Ejemplares similares