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Immunization with Recombinant TcdB-Encapsulated Nanocomplex Induces Protection against Clostridium difficile Challenge in a Mouse Model

Clostridium difficile is considered to be one of the major cause of infectious diarrhea in healthcare systems worldwide. Symptoms of C. difficile infection are caused largely by the production of two cytotoxins: toxin A (TcdA) and toxin B (TcdB). Vaccine development is considered desirable as it wou...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Wen, Chen, Yu-Hung, Chen, Jenn-Wei, Tsai, Pei-Jane, Huang, I-Hsiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525027/
https://www.ncbi.nlm.nih.gov/pubmed/28790999
http://dx.doi.org/10.3389/fmicb.2017.01411

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