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Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury

BACKGROUND: FTY720 (fingolimod, Gilenya™) is an oral, blood-brain barrier (BBB)-passing drug approved as immunomodulatory treatment for relapsing-remitting form of the multiple sclerosis (MS). In addition, FTY720 exerts several effects in the central nervous system (CNS), ranging from neuroprotectio...

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Detalles Bibliográficos
Autores principales: Cipriani, Raffaela, Chara, Juan Carlos, Rodríguez-Antigüedad, Alfredo, Matute, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525223/
https://www.ncbi.nlm.nih.gov/pubmed/28738875
http://dx.doi.org/10.1186/s12974-017-0922-6