Cargando…

TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders

BACKGROUND: Inflammation during brain development participates in the pathogenesis of early brain injury and cognitive dysfunctions. Prenatal ethanol exposure affects the developing brain and causes neural impairment, cognitive and behavioral effects, collectively known as fetal alcohol spectrum dis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pascual, María, Montesinos, Jorge, Montagud-Romero, Sandra, Forteza, Jerónimo, Rodríguez-Arias, Marta, Miñarro, José, Guerri, Consuelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525270/ https://www.ncbi.nlm.nih.gov/pubmed/28738878 http://dx.doi.org/10.1186/s12974-017-0918-2

Ejemplares similares

TLR4 participates in the transmission of ethanol-induced neuroinflammation via astrocyte-derived extracellular vesicles
por: Ibáñez, Francesc, et al.
Publicado: (2019)

Ethanol Induces Extracellular Vesicle Secretion by Altering Lipid Metabolism through the Mitochondria-Associated ER Membranes and Sphingomyelinases
por: Ibáñez, Francesc, et al.
Publicado: (2021)

Role of mTOR‐regulated autophagy in spine pruning defects and memory impairments induced by binge‐like ethanol treatment in adolescent mice
por: Pascual, María, et al.
Publicado: (2020)

Glia and Neurodevelopment: Focus on Fetal Alcohol Spectrum Disorders
por: Guizzetti, Marina, et al.
Publicado: (2014)

Corrigendum: “Glia and Neurodevelopment: Focus on Fetal Alcohol Spectrum Disorders”
por: Guizzetti, Marina, et al.
Publicado: (2015)

Therapeutic role of mesenchymal stem cell‐derived extracellular vesicles in neuroinflammation and cognitive dysfunctions induced by binge‐like ethanol treatment in adolescent mice
por: Mellado, Susana, et al.
Publicado: (2023)

Ketogenic Diet Decreases Alcohol Intake in Adult Male Mice
por: Blanco-Gandía, María del Carmen, et al.
Publicado: (2021)

Ethanol Exposure Alters Protein Expression in a Mouse Model of Fetal Alcohol Spectrum Disorders
por: Mason, Stephen, et al.
Publicado: (2012)

Autophagy Constitutes a Protective Mechanism against Ethanol Toxicity in Mouse Astrocytes and Neurons
por: Pla, Antoni, et al.
Publicado: (2016)

The Novelty-Seeking Phenotype Modulates the Long-Lasting Effects of Intermittent Ethanol Administration during Adolescence
por: Montagud-Romero, Sandra, et al.
Publicado: (2014)

Pairing Binge Drinking and a High-Fat Diet in Adolescence Modulates the Inflammatory Effects of Subsequent Alcohol Consumption in Mice
por: González-Portilla, Macarena, et al.
Publicado: (2021)

TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain
por: Pla, A, et al.
Publicado: (2014)

Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder
por: Wozniak, Jeffrey R., et al.
Publicado: (2020)

TLR4 Deficiency Affects the Microbiome and Reduces Intestinal Dysfunctions and Inflammation in Chronic Alcohol-Fed Mice
por: Cuesta, Carlos M., et al.
Publicado: (2021)

Breaking In through Critical Windows: p,p′-DDE May Alter Fetal Neurodevelopment
por: Barrett, Julia R.
Publicado: (2007)

Editorial: Unraveling vulnerability factors in addiction drug use and potential treatments
por: Montesinos, Jorge, et al.
Publicado: (2022)

The maternal microbiome modulates fetal neurodevelopment in mice
por: Vuong, H. E., et al.
Publicado: (2020)

Gestational Factors throughout Fetal Neurodevelopment: The Serotonin Link
por: Hanswijk, Sabrina I., et al.
Publicado: (2020)

Intrauterine Viral Infections: Impact of Inflammation on Fetal Neurodevelopment
por: Ganguli, Sourav, et al.
Publicado: (2021)

Oleoylethanolamide attenuates cocaine-primed reinstatement and alters dopaminergic gene expression in the striatum
por: González-Portilla, Macarena, et al.
Publicado: (2023)

Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression
por: Jaini, Ritika, et al.
Publicado: (2021)

Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
por: Holloway, Kalee N., et al.
Publicado: (2023)

Intersection of Epigenetic and Immune Alterations: Implications for Fetal Alcohol Spectrum Disorder and Mental Health
por: Lussier, Alexandre A., et al.
Publicado: (2021)

Increased ethanol consumption after interruption of fat bingeing
por: Blanco-Gandía, M. Carmen, et al.
Publicado: (2018)

Long-term follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder: corpus callosum white matter microstructure and neurocognitive outcomes
por: Gimbel, Blake A., et al.
Publicado: (2022)

Eyeblink Classical Conditioning in Alcoholism and Fetal Alcohol Spectrum Disorders
por: Cheng, Dominic T., et al.
Publicado: (2015)

Focus On: Epigenetics and Fetal Alcohol Spectrum Disorders
por: Kobor, Michael S., et al.
Publicado: (2011)

Oligodendrocyte pathology in fetal alcohol spectrum disorders
por: Darbinian, Nune, et al.
Publicado: (2021)

Fetal Alcohol Spectrum Disorder in a Newborn
por: Patel, Tejal, et al.
Publicado: (2022)

Fetal Alcohol Spectrum Disorder and Iron Homeostasis
por: Bradley, Regan, et al.
Publicado: (2022)

Genetic Influences on Fetal Alcohol Spectrum Disorder
por: Sambo, Danielle, et al.
Publicado: (2023)

The Prevalence of Fetal Alcohol Spectrum Disorders in An American Indian Community
por: Montag, Annika C., et al.
Publicado: (2019)

Corrigendum: Intrauterine Viral Infections: Impact of Inflammation on Fetal Neurodevelopment
por: Ganguli, Sourav, et al.
Publicado: (2021)

Lack of TLR4 modifies the miRNAs profile and attenuates inflammatory signaling pathways
por: Ureña-Peralta, Juan R., et al.
Publicado: (2020)

Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy
por: Gilbert-Jaramillo, Javier, et al.
Publicado: (2023)

Indomethacin blocks the increased conditioned rewarding effects of cocaine induced by repeated social defeat
por: Ferrer-Pérez, Carmen, et al.
Publicado: (2018)

Correction: Indomethacin blocks the increased conditioned rewarding effects of cocaine induced by repeated social defeat
por: Ferrer-Pérez, Carmen, et al.
Publicado: (2019)

Effect of intermittent exposure to ethanol and MDMA during adolescence on learning and memory in adult mice
por: Vidal-Infer, Antonio, et al.
Publicado: (2012)

The Mechanisms of CHD8 in Neurodevelopment and Autism Spectrum Disorders
por: Weissberg, Orly, et al.
Publicado: (2021)

Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder
por: Camargo Moreno, Maria, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4bggcu31v59ugcirhgo0rsltc6