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A long-range interactive DNA methylation marker panel for the promoters of HOXA9 and HOXA10 predicts survival in breast cancer patients

BACKGROUND: Most DNA cancer methylation markers are based on the transcriptional regulation of the promoter-gene relationship. Recently, the importance of long-range interactions between distal CpGs and target genes has been revealed. Here, we attempted to identify methylation markers for breast can...

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Detalles Bibliográficos
Autores principales: Park, Seong-Min, Choi, Eun-Young, Bae, Mingyun, Choi, Jung Kyoon, Kim, Youn-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525292/
https://www.ncbi.nlm.nih.gov/pubmed/28748001
http://dx.doi.org/10.1186/s13148-017-0373-z