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Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40(+) monocyte differentiation

Adaptive immunity is critical for disease progression and modulates T cell (TC) and antigen-presenting cell (APC) functions. Three signals were initially proposed for adaptive immune activation: signal 1 antigen recognition, signal 2 co-stimulation or co-inhibition, and signal 3 cytokine stimulation...

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Detalles Bibliográficos
Autores principales: Dai, Jin, Fang, Pu, Saredy, Jason, Xi, Hang, Ramon, Cueto, Yang, William, Choi, Eric T., Ji, Yong, Mao, Wei, Yang, Xiaofeng, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525309/
https://www.ncbi.nlm.nih.gov/pubmed/28738836
http://dx.doi.org/10.1186/s13045-017-0504-1