Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis

BACKGROUND: MP4-induced experimental autoimmune encephalomyelitis (EAE) is a mouse model of multiple sclerosis (MS), which enables targeted research on B cells, currently much discussed protagonists in MS pathogenesis. Here, we used this model to study the impact of the S1P(1) receptor modulator FTY...

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Detalles Bibliográficos
Autores principales: Bail, Kathrin, Notz, Quirin, Rovituso, Damiano M., Schampel, Andrea, Wunsch, Marie, Koeniger, Tobias, Schropp, Verena, Bharti, Richa, Scholz, Claus-Juergen, Foerstner, Konrad U., Kleinschnitz, Christoph, Kuerten, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525315/
https://www.ncbi.nlm.nih.gov/pubmed/28738885
http://dx.doi.org/10.1186/s12974-017-0924-4

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