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Resampling-based tests for Lasso in genome-wide association studies
BACKGROUND: Genome-wide association studies involve detecting association between millions of genetic variants and a trait, which typically use univariate regression to test association between each single variant and the phenotype. Alternatively, Lasso penalized regression allows one to jointly mod...
Autores principales: | Arbet, Jaron, McGue, Matt, Chatterjee, Snigdhansu, Basu, Saonli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525347/ https://www.ncbi.nlm.nih.gov/pubmed/28738830 http://dx.doi.org/10.1186/s12863-017-0533-3 |
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