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Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525485/ https://www.ncbi.nlm.nih.gov/pubmed/28272065 http://dx.doi.org/10.4103/0022-3859.201413 |
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author | Gupta, A Reddy, GK Goyal, M Kasaragadda, MR |
author_facet | Gupta, A Reddy, GK Goyal, M Kasaragadda, MR |
author_sort | Gupta, A |
collection | PubMed |
description | Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision. |
format | Online Article Text |
id | pubmed-5525485 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-55254852017-08-08 Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) Gupta, A Reddy, GK Goyal, M Kasaragadda, MR J Postgrad Med Case Report Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5525485/ /pubmed/28272065 http://dx.doi.org/10.4103/0022-3859.201413 Text en Copyright: © 2017 Journal of Postgraduate Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Gupta, A Reddy, GK Goyal, M Kasaragadda, MR Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) |
title | Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) |
title_full | Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) |
title_fullStr | Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) |
title_full_unstemmed | Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) |
title_short | Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) |
title_sort | erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525485/ https://www.ncbi.nlm.nih.gov/pubmed/28272065 http://dx.doi.org/10.4103/0022-3859.201413 |
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