Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)

Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with...

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Autores principales: Gupta, A, Reddy, GK, Goyal, M, Kasaragadda, MR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525485/
https://www.ncbi.nlm.nih.gov/pubmed/28272065
http://dx.doi.org/10.4103/0022-3859.201413
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author Gupta, A
Reddy, GK
Goyal, M
Kasaragadda, MR
author_facet Gupta, A
Reddy, GK
Goyal, M
Kasaragadda, MR
author_sort Gupta, A
collection PubMed
description Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision.
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spelling pubmed-55254852017-08-08 Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16) Gupta, A Reddy, GK Goyal, M Kasaragadda, MR J Postgrad Med Case Report Erythrophagocytosis by leukemic blasts is a rare phenomenon. We report a case of a female diagnosed with acute monoblastic leukemia with leukemic blasts that were CD34 and CD117 negative, showing erythrophagocytosis, vacoulations, and a rare t(8;16) on bone marrow karyotype which is associated with a poor prognosis despite intensive chemotherapy. Meticulous bone marrow examination in such a scenario may point towards the presence of t(8;16) and help clinicians take a well-informed clinical decision. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5525485/ /pubmed/28272065 http://dx.doi.org/10.4103/0022-3859.201413 Text en Copyright: © 2017 Journal of Postgraduate Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gupta, A
Reddy, GK
Goyal, M
Kasaragadda, MR
Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_full Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_fullStr Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_full_unstemmed Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_short Erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
title_sort erythrophagocytosis by blasts in a case of de novo acute monoblastic leukemia with rare but characteristic t(8;16)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525485/
https://www.ncbi.nlm.nih.gov/pubmed/28272065
http://dx.doi.org/10.4103/0022-3859.201413
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AT goyalm erythrophagocytosisbyblastsinacaseofdenovoacutemonoblasticleukemiawithrarebutcharacteristict816
AT kasaragaddamr erythrophagocytosisbyblastsinacaseofdenovoacutemonoblasticleukemiawithrarebutcharacteristict816

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