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Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency

PURPOSE: Photoreceptor degeneration in the retina is a major cause of blindness in humans. Elucidating mechanisms of degenerative and neuroprotective pathways in photoreceptors should afford identification and development of therapeutic strategies. METHODS: We used mouse genetic models and improved...

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Detalles Bibliográficos
Autores principales:	Nagar, Saumya, Trudler, Dorit, McKercher, Scott R., Piña-Crespo, Juan, Nakanishi, Nobuki, Okamoto, Shu-Ichi, Lipton, Stuart A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2017
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525556/ https://www.ncbi.nlm.nih.gov/pubmed/28738418 http://dx.doi.org/10.1167/iovs.17-21767

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