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The MalR type regulator AcrC is a transcriptional repressor of acarbose biosynthetic genes in Actinoplanes sp. SE50/110

BACKGROUND: Acarbose is used in the treatment of diabetes mellitus type II and is produced by Actinoplanes sp. SE50/110. Although the biosynthesis of acarbose has been intensively studied, profound knowledge about transcription factors involved in acarbose biosynthesis and their binding sites has be...

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Detalles Bibliográficos
Autores principales:	Wolf, Timo, Droste, Julian, Gren, Tetiana, Ortseifen, Vera, Schneiker-Bekel, Susanne, Zemke, Till, Pühler, Alfred, Kalinowski, Jörn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526262/ https://www.ncbi.nlm.nih.gov/pubmed/28743243 http://dx.doi.org/10.1186/s12864-017-3941-x

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