Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A

OBJECTIVE—: To establish the cellular source of plasma factor (F)XIII-A. APPROACH AND RESULTS—: A novel mouse floxed for the F13a1 gene, FXIII-A(flox/flox) (Flox), was crossed with myeloid- and platelet-cre–expressing mice, and cellular FXIII-A mRNA expression and plasma and platelet FXIII-A levels...

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Detalles Bibliográficos
Autores principales: Beckers, Cora M.L., Simpson, Kingsley R., Griffin, Kathryn J., Brown, Jane M., Cheah, Lih T., Smith, Kerrie A., Vacher, Jean, Cordell, Paul A., Kearney, Mark T., Grant, Peter J., Pease, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526434/
https://www.ncbi.nlm.nih.gov/pubmed/28596376
http://dx.doi.org/10.1161/ATVBAHA.117.309271

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