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Comprehensive immune profiling reveals substantial immune system alterations in a subset of patients with amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a median lifespan of 2–3 years after diagnosis. There are few meaningful treatments that alter progression in this disease. Preclinical and clinical studies have demonstrated that neuroinflammation may play a key role in t...
Autores principales: | Gustafson, Michael P., Staff, Nathan P., Bornschlegl, Svetlana, Butler, Greg W., Maas, Mary L., Kazamel, Mohamed, Zubair, Adeel, Gastineau, Dennis A., Windebank, Anthony J., Dietz, Allan B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526569/ https://www.ncbi.nlm.nih.gov/pubmed/28742871 http://dx.doi.org/10.1371/journal.pone.0182002 |
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