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Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection

AIM: To find an accurate and simple predictor for postoperative short-term complications after gastrectomy. METHODS: Two hundred and twenty-three patients undergoing gastric cancer resection between October 1, 2015 and September 30, 2016 were enrolled in this study. Univariate and multivariate analy...

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Autores principales: Liu, Zhi-Jian, Ge, Xiao-Long, Ai, Shi-Chao, Wang, Hong-Kan, Sun, Feng, Chen, Li, Guan, Wen-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526768/
https://www.ncbi.nlm.nih.gov/pubmed/28785152
http://dx.doi.org/10.3748/wjg.v23.i27.4978
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author Liu, Zhi-Jian
Ge, Xiao-Long
Ai, Shi-Chao
Wang, Hong-Kan
Sun, Feng
Chen, Li
Guan, Wen-Xian
author_facet Liu, Zhi-Jian
Ge, Xiao-Long
Ai, Shi-Chao
Wang, Hong-Kan
Sun, Feng
Chen, Li
Guan, Wen-Xian
author_sort Liu, Zhi-Jian
collection PubMed
description AIM: To find an accurate and simple predictor for postoperative short-term complications after gastrectomy. METHODS: Two hundred and twenty-three patients undergoing gastric cancer resection between October 1, 2015 and September 30, 2016 were enrolled in this study. Univariate and multivariate analyses were used to identify risk factors for complications after gastrectomy. The cutoff values and diagnostic accuracy were examined by receiver operating characteristic curves. RESULTS: Sixty-two (27.8%) patients had short-term complications after gastric cancer resection. The postoperative decrease in serum albumin (∆ALB) was an independent risk factor for complications (OR = 17.957, 95%CI: 6.073-53.095, P < 0.001). The cutoff value was 14.0% and the area under the curve was higher than that of C-reactive protein on postoperative day 3 (area under the curve: 0.806 vs 0.709). Patients with ∆ALB ≥ 14.0% were more likely to have short-term complications after gastrectomy (46.7% vs 5.0%, P < 0.001), prolonged hospital stay (17.2 ± 10.8 d vs 14.1 ± 4.2 d, P = 0.007) and higher comprehensive complication index (P < 0.001) than those with ∆ALB < 14.0%. CONCLUSION: Postoperative ∆ALB with a cutoff of 14.0% can be used to recognize patients who have high risk of short-term complications following gastric cancer resection.
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spelling pubmed-55267682017-08-07 Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection Liu, Zhi-Jian Ge, Xiao-Long Ai, Shi-Chao Wang, Hong-Kan Sun, Feng Chen, Li Guan, Wen-Xian World J Gastroenterol Prospective Study AIM: To find an accurate and simple predictor for postoperative short-term complications after gastrectomy. METHODS: Two hundred and twenty-three patients undergoing gastric cancer resection between October 1, 2015 and September 30, 2016 were enrolled in this study. Univariate and multivariate analyses were used to identify risk factors for complications after gastrectomy. The cutoff values and diagnostic accuracy were examined by receiver operating characteristic curves. RESULTS: Sixty-two (27.8%) patients had short-term complications after gastric cancer resection. The postoperative decrease in serum albumin (∆ALB) was an independent risk factor for complications (OR = 17.957, 95%CI: 6.073-53.095, P < 0.001). The cutoff value was 14.0% and the area under the curve was higher than that of C-reactive protein on postoperative day 3 (area under the curve: 0.806 vs 0.709). Patients with ∆ALB ≥ 14.0% were more likely to have short-term complications after gastrectomy (46.7% vs 5.0%, P < 0.001), prolonged hospital stay (17.2 ± 10.8 d vs 14.1 ± 4.2 d, P = 0.007) and higher comprehensive complication index (P < 0.001) than those with ∆ALB < 14.0%. CONCLUSION: Postoperative ∆ALB with a cutoff of 14.0% can be used to recognize patients who have high risk of short-term complications following gastric cancer resection. Baishideng Publishing Group Inc 2017-07-21 2017-07-21 /pmc/articles/PMC5526768/ /pubmed/28785152 http://dx.doi.org/10.3748/wjg.v23.i27.4978 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Prospective Study
Liu, Zhi-Jian
Ge, Xiao-Long
Ai, Shi-Chao
Wang, Hong-Kan
Sun, Feng
Chen, Li
Guan, Wen-Xian
Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection
title Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection
title_full Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection
title_fullStr Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection
title_full_unstemmed Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection
title_short Postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection
title_sort postoperative decrease of serum albumin predicts short-term complications in patients undergoing gastric cancer resection
topic Prospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526768/
https://www.ncbi.nlm.nih.gov/pubmed/28785152
http://dx.doi.org/10.3748/wjg.v23.i27.4978
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