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The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1

Faithful propagation of functionally distinct chromatin states is crucial for maintaining cellular identity, and its breakdown can lead to diseases such as cancer. Whereas mechanisms that sustain repressed states have been intensely studied, regulatory circuits that protect active chromatin from ina...

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Detalles Bibliográficos
Autores principales: Flury, Valentin, Georgescu, Paula Raluca, Iesmantavicius, Vytautas, Shimada, Yukiko, Kuzdere, Tahsin, Braun, Sigurd, Bühler, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526834/
https://www.ncbi.nlm.nih.gov/pubmed/28648780
http://dx.doi.org/10.1016/j.molcel.2017.05.026