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The Histone Acetyltransferase Mst2 Protects Active Chromatin from Epigenetic Silencing by Acetylating the Ubiquitin Ligase Brl1
Faithful propagation of functionally distinct chromatin states is crucial for maintaining cellular identity, and its breakdown can lead to diseases such as cancer. Whereas mechanisms that sustain repressed states have been intensely studied, regulatory circuits that protect active chromatin from ina...
Autores principales: | Flury, Valentin, Georgescu, Paula Raluca, Iesmantavicius, Vytautas, Shimada, Yukiko, Kuzdere, Tahsin, Braun, Sigurd, Bühler, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526834/ https://www.ncbi.nlm.nih.gov/pubmed/28648780 http://dx.doi.org/10.1016/j.molcel.2017.05.026 |
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