l-Arginine Uptake by Cationic Amino Acid Transporter Promotes Intra-Macrophage Survival of Leishmania donovani by Enhancing Arginase-Mediated Polyamine Synthesis

The survival of intracellular protozoan parasite, Leishmania donovani, the causative agent of Indian visceral leishmaniasis (VL), depends on the activation status of macrophages. l-Arginine, a semi-essential amino acid plays a crucial regulatory role for activation of macrophages. However, the role...

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Detalles Bibliográficos
Autores principales: Mandal, Abhishek, Das, Sushmita, Kumar, Ajay, Roy, Saptarshi, Verma, Sudha, Ghosh, Ayan Kumar, Singh, Ruby, Abhishek, Kumar, Saini, Savita, Sardar, Abul Hasan, Purkait, Bidyut, Kumar, Ashish, Mandal, Chitra, Das, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526900/
https://www.ncbi.nlm.nih.gov/pubmed/28798743
http://dx.doi.org/10.3389/fimmu.2017.00839

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