MicroRNA-200b regulates distal airway development by maintaining epithelial integrity

miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a lower number of airway generations, and a thicker mesenchyme...

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Detalles Bibliográficos
Autores principales: Khoshgoo, Naghmeh, Visser, Robin, Falk, Landon, Day, Chelsea A., Ameis, Dustin, Iwasiow, Barbara M., Zhu, Fuqin, Öztürk, Arzu, Basu, Sujata, Pind, Molly, Fresnosa, Agnes, Jackson, Mike, Siragam, Vinaya Kumar, Stelmack, Gerald, Hicks, Geoffrey G., Halayko, Andrew J., Keijzer, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526907/
https://www.ncbi.nlm.nih.gov/pubmed/28743913
http://dx.doi.org/10.1038/s41598-017-05412-y

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