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Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis

Knowledge about the region-specific absorption profiles from the gastrointestinal tract of orally administered drugs is a critical factor guiding dosage form selection in drug development. We have used a novel approach to study three well-characterized permeability and absorption marker drugs in the...

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Detalles Bibliográficos
Autores principales:	Nilsson, Anna, Peric, Alexandra, Strimfors, Marie, Goodwin, Richard J. A., Hayes, Martin A., Andrén, Per E., Hilgendorf, Constanze
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526999/ https://www.ncbi.nlm.nih.gov/pubmed/28743866 http://dx.doi.org/10.1038/s41598-017-06583-4

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