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Public variant databases: liability?
Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527130/ https://www.ncbi.nlm.nih.gov/pubmed/27977006 http://dx.doi.org/10.1038/gim.2016.189 |
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author | Thorogood, Adrian Cook-Deegan, Robert Knoppers, Bartha Maria |
author_facet | Thorogood, Adrian Cook-Deegan, Robert Knoppers, Bartha Maria |
author_sort | Thorogood, Adrian |
collection | PubMed |
description | Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing. Genet Med advance online publication 15 December 2016 |
format | Online Article Text |
id | pubmed-5527130 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-55271302017-12-02 Public variant databases: liability? Thorogood, Adrian Cook-Deegan, Robert Knoppers, Bartha Maria Genet Med Special Article Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing. Genet Med advance online publication 15 December 2016 Nature Publishing Group 2017-07 2016-12-15 /pmc/articles/PMC5527130/ /pubmed/27977006 http://dx.doi.org/10.1038/gim.2016.189 Text en Copyright © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Special Article Thorogood, Adrian Cook-Deegan, Robert Knoppers, Bartha Maria Public variant databases: liability? |
title | Public variant databases: liability? |
title_full | Public variant databases: liability? |
title_fullStr | Public variant databases: liability? |
title_full_unstemmed | Public variant databases: liability? |
title_short | Public variant databases: liability? |
title_sort | public variant databases: liability? |
topic | Special Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527130/ https://www.ncbi.nlm.nih.gov/pubmed/27977006 http://dx.doi.org/10.1038/gim.2016.189 |
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