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Public variant databases: liability?

Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients...

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Detalles Bibliográficos
Autores principales: Thorogood, Adrian, Cook-Deegan, Robert, Knoppers, Bartha Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527130/
https://www.ncbi.nlm.nih.gov/pubmed/27977006
http://dx.doi.org/10.1038/gim.2016.189
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author Thorogood, Adrian
Cook-Deegan, Robert
Knoppers, Bartha Maria
author_facet Thorogood, Adrian
Cook-Deegan, Robert
Knoppers, Bartha Maria
author_sort Thorogood, Adrian
collection PubMed
description Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing. Genet Med advance online publication 15 December 2016
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spelling pubmed-55271302017-12-02 Public variant databases: liability? Thorogood, Adrian Cook-Deegan, Robert Knoppers, Bartha Maria Genet Med Special Article Public variant databases support the curation, clinical interpretation, and sharing of genomic data, thus reducing harmful errors or delays in diagnosis. As variant databases are increasingly relied on in the clinical context, there is concern that negligent variant interpretation will harm patients and attract liability. This article explores the evolving legal duties of laboratories, public variant databases, and physicians in clinical genomics and recommends a governance framework for databases to promote responsible data sharing. Genet Med advance online publication 15 December 2016 Nature Publishing Group 2017-07 2016-12-15 /pmc/articles/PMC5527130/ /pubmed/27977006 http://dx.doi.org/10.1038/gim.2016.189 Text en Copyright © 2016 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Special Article
Thorogood, Adrian
Cook-Deegan, Robert
Knoppers, Bartha Maria
Public variant databases: liability?
title Public variant databases: liability?
title_full Public variant databases: liability?
title_fullStr Public variant databases: liability?
title_full_unstemmed Public variant databases: liability?
title_short Public variant databases: liability?
title_sort public variant databases: liability?
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527130/
https://www.ncbi.nlm.nih.gov/pubmed/27977006
http://dx.doi.org/10.1038/gim.2016.189
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