Development and Optimization of a New Chemoenzymatic Approach for the Synthesis of Peracetylated Lactosamine (Intermediate for the Synthesis of Pharmacologically Active Compounds) Monitored by RP- HPLC Method

Purpose: To describe a chemoenzymatic approach joining an enzymatic regioselective hydrolysis of peracetylated N-acetyl-α-D-glucosamine (A) with a mild controlled acyl relocation which resulted 2-acetamido-2 deoxy-1,3,6-tri-O-acetyl-α-D-glucopyranose (1B). Methods: Immobilization of lipase on decaoc...

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Detalles Bibliográficos
Autores principales: Abualassal, Qais Ibrahim, Al Azzam, Khaldun Mohammad, Abudayeh, Zead Helmi, Hassouneh, Loay Khaled
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527246/
https://www.ncbi.nlm.nih.gov/pubmed/28761834
http://dx.doi.org/10.15171/apb.2017.037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527246/
https://www.ncbi.nlm.nih.gov/pubmed/28761834
http://dx.doi.org/10.15171/apb.2017.037

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