BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease

Epicardium-derived cells (EPDCs) contribute cardiovascular cell types during development and in adulthood respond to Thymosin β4 (Tβ4) and myocardial infarction (MI) by reactivating a fetal gene programme to promote neovascularization and cardiomyogenesis. The mechanism for epicardial gene (re-)acti...

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Detalles Bibliográficos
Autores principales: Vieira, Joaquim Miguel, Howard, Sara, Villa del Campo, Cristina, Bollini, Sveva, Dubé, Karina N., Masters, Megan, Barnette, Damien N., Rohling, Mala, Sun, Xin, Hankins, Laura E., Gavriouchkina, Daria, Williams, Ruth, Metzger, Daniel, Chambon, Pierre, Sauka-Spengler, Tatjana, Davies, Benjamin, Riley, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527284/
https://www.ncbi.nlm.nih.gov/pubmed/28737171
http://dx.doi.org/10.1038/ncomms16034

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