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Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC

The infectious diseases caused by multidrug-resistant bacteria pose serious threats to humankind. It has been suggested that an antibiotic targeting LpxC of the lipid A biosynthetic pathway in Gram-negative bacteria is a promising strategy for curing Gram-negative bacterial infections. However, expe...

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Detalles Bibliográficos
Autores principales:	Lemaître, Nadine, Liang, Xiaofei, Najeeb, Javaria, Lee, Chul-Jin, Titecat, Marie, Leteurtre, Emmanuelle, Simonet, Michel, Toone, Eric J., Zhou, Pei, Sebbane, Florent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527309/ https://www.ncbi.nlm.nih.gov/pubmed/28743813 http://dx.doi.org/10.1128/mBio.00674-17

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