Cargando…

Multi‐parametric profiling of renal cell, colorectal, and ovarian cancer identifies tumour‐type‐specific stroma phenotypes and a novel vascular biomarker

A novel set of integrated procedures for quantification of fibroblast‐rich stroma and vascular characteristics has recently been presented allowing discovery of novel perivascular and stromal biomarkers in colorectal, renal cell, and ovarian cancer. In the present study, data obtained through these...

Descripción completa

Detalles Bibliográficos
Autores principales:	Corvigno, Sara, Frödin, Magnus, Wisman, G Bea A, Nijman, Hans W, Van der Zee, Ate GJ, Jirström, Karin, Nodin, Björn, Hrynchyk, Ina, Edler, David, Ragnhammar, Peter, Johansson, Martin, Dahlstrand, Hanna, Mezheyeuski, Artur, Östman, Arne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527322/ https://www.ncbi.nlm.nih.gov/pubmed/28770105 http://dx.doi.org/10.1002/cjp2.74

Ejemplares similares

Markers of fibroblast-rich tumor stroma and perivascular cells in serous ovarian cancer: Inter- and intra-patient heterogeneity and impact on survival
por: Corvigno, Sara, et al.
Publicado: (2016)

Stroma-normalised vessel density predicts benefit from adjuvant fluorouracil-based chemotherapy in patients with stage II/III colon cancer
por: Mezheyeuski, Artur, et al.
Publicado: (2019)

Image analysis-derived metrics of histomorphological complexity predicts prognosis and treatment response in stage II-III colon cancer
por: Mezheyeuski, Artur, et al.
Publicado: (2016)

Perivascular PDGFR-β is an independent marker for prognosis in renal cell carcinoma
por: Frödin, Magnus, et al.
Publicado: (2017)

Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma
por: Lundgren, Sebastian, et al.
Publicado: (2020)

A minority-group of renal cell cancer patients with high infiltration of CD20+B-cells is associated with poor prognosis
por: Sjöberg, Elin, et al.
Publicado: (2018)

The prognostic impact of the tumour stroma fraction: A machine learning-based analysis in 16 human solid tumour types
por: Micke, Patrick, et al.
Publicado: (2021)

Fibroblasts in urothelial bladder cancer define stroma phenotypes that are associated with clinical outcome
por: Mezheyeuski, Artur, et al.
Publicado: (2020)

Expression of the chemokine CXCL14 in the tumour stroma is an independent marker of survival in breast cancer
por: Sjöberg, Elin, et al.
Publicado: (2016)

Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer
por: Mezheyeuski, Artur, et al.
Publicado: (2017)

Prognostic Interactions between FAP+ Fibroblasts and CD8a+ T Cells in Colon Cancer
por: Herrera, Mercedes, et al.
Publicado: (2020)

Discovery of DNA methylation markers in cervical cancer using relaxation ranking
por: Ongenaert, Maté, et al.
Publicado: (2008)

Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC
por: Strell, Carina, et al.
Publicado: (2017)

Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and pathways
por: Tomar, Tushar, et al.
Publicado: (2016)

DNA methylation markers as a triage test for identification of cervical lesions in a high risk human papillomavirus positive screening cohort
por: van Leeuwen, Robert W., et al.
Publicado: (2018)

An Overview of Innovative Techniques to Improve Cervical Cancer Screening
por: Nijhuis, Esther R., et al.
Publicado: (2006)

DNA methylation markers as triage test for the early identification of cervical lesions in a Chinese population
por: Li, Na, et al.
Publicado: (2020)

The Immune Landscape of Colorectal Cancer
por: Mezheyeuski, Artur, et al.
Publicado: (2021)

Clinicopathological correlates and prognostic significance of KRAS mutation status in a pooled prospective cohort of epithelial ovarian cancer
por: Nodin, Björn, et al.
Publicado: (2013)

Biobanking of patient and patient-derived xenograft ovarian tumour tissue: efficient preservation with low and high fetal calf serum based methods
por: Alkema, Nicolette G., et al.
Publicado: (2015)

Proteomic alterations in early stage cervical cancer
por: Güzel, Coşkun, et al.
Publicado: (2018)

An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
por: Mezheyeuski, Artur, et al.
Publicado: (2023)

Survival-associated heterogeneity of marker-defined perivascular cells in colorectal cancer
por: Mezheyeuski, Artur, et al.
Publicado: (2016)

Vessel size as a marker of survival in estrogen receptor positive breast cancer
por: Milosevic, Vladan, et al.
Publicado: (2023)

The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
por: Medrek, Catharina, et al.
Publicado: (2012)

A PDGFRB- and CD40-targeting bispecific AffiMab induces stroma-targeted immune cell activation
por: Mega, Alessandro, et al.
Publicado: (2023)

Remodeling of Tumor Stroma and Response to Therapy
por: Johansson, Anna, et al.
Publicado: (2012)

Associations of Anthropometric Factors with KRAS and BRAF Mutation Status of Primary Colorectal Cancer in Men and Women: A Cohort Study
por: Brändstedt, Jenny, et al.
Publicado: (2014)

Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer
por: Fedoseienko, Alina, et al.
Publicado: (2016)

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma
por: Wang, Rong, et al.
Publicado: (2016)

Mesothelin Expression in Patients with High-Grade Serous Ovarian Cancer Does Not Predict Clinical Outcome But Correlates with CD11c(+) Expression in Tumor
por: Magalhaes, Isabelle, et al.
Publicado: (2020)

Expression of cartilage oligomeric matrix protein in periampullary adenocarcinoma is associated with pancreatobiliary-type morphology, higher levels of fibrosis and immune cell exclusion
por: Papadakos, Konstantinos S., et al.
Publicado: (2022)

High Density of NRF2 Expression in Malignant Cells Is Associated with Increased Risk of CNS Metastasis in Early-Stage NSCLC
por: Tsakonas, Georgios, et al.
Publicado: (2021)

Discovery of dachshund 2 protein as a novel biomarker of poor prognosis in epithelial ovarian cancer
por: Nodin, Björn, et al.
Publicado: (2012)

Expression of the global regulator SATB1 is an independent factor of poor prognosis in high grade epithelial ovarian cancer
por: Nodin, Björn, et al.
Publicado: (2012)

Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study
por: Wangefjord, Sakarias, et al.
Publicado: (2013)

Prognostic and predictive impact of stroma cells defined by PDGFRb expression in early breast cancer: results from the randomized SweBCG91RT trial
por: Strell, Carina, et al.
Publicado: (2021)

Familial Cervical Cancer: Case Reports, Review and Clinical Implications
por: Zoodsma, Margreet, et al.
Publicado: (2004)

The role of ATM and 53BP1 as predictive markers in cervical cancer
por: Roossink, Frank, et al.
Publicado: (2012)

Tumor-Associated CD68(+), CD163(+), and MARCO(+) Macrophages as Prognostic Biomarkers in Patients With Treatment-Naïve Gastroesophageal Adenocarcinoma
por: Jeremiasen, Martin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7601583dlu69fme8p1veo6db8h