NMR metabolomics highlights sphingosine kinase‐1 as a new molecular switch in the orchestration of aberrant metabolic phenotype in cancer cells

Strong experimental evidence in animal and cellular models supports a pivotal role of sphingosine kinase‐1 (SK1) in oncogenesis. In many human cancers, SK1 levels are upregulated and these increases are linked to poor prognosis in patients. Here, by employing untargeted NMR‐based metabolomic profili...

Descripción completa

Detalles Bibliográficos
Autores principales: Bernacchioni, Caterina, Ghini, Veronica, Cencetti, Francesca, Japtok, Lukasz, Donati, Chiara, Bruni, Paola, Turano, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527469/
https://www.ncbi.nlm.nih.gov/pubmed/28258651
http://dx.doi.org/10.1002/1878-0261.12048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527469/
https://www.ncbi.nlm.nih.gov/pubmed/28258651
http://dx.doi.org/10.1002/1878-0261.12048

Ejemplares similares