Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B

Leishmaniasis is a disease found throughout the (sub)tropical parts of the world caused by protozoan parasites of the Leishmania genus. Despite the numerous problems associated with existing treatments, pharmaceutical companies continue to neglect the development of better ones. The high toxicity of...

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Detalles Bibliográficos
Autores principales: Velásquez, Angela Maria Arenas, Ribeiro, Willian Campos, Venn, Vutey, Castelli, Silvia, de Camargo, Mariana Santoro, de Assis, Renata Pires, de Souza, Rodrigo Alves, Ribeiro, Aline Rimoldi, Passalacqua, Thaís Gaban, da Rosa, João Aristeu, Baviera, Amanda Martins, Mauro, Antonio Eduardo, Desideri, Alessandro, Almeida-Amaral, Elmo Eduardo, Graminha, Marcia A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527659/
https://www.ncbi.nlm.nih.gov/pubmed/28507113
http://dx.doi.org/10.1128/AAC.00688-17

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