Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation

A young man suffered cardiac arrests with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF) triggered by ventricular premature contractions (PVCs). The arrhythmia was resistant to anti-arrhythmics, so after ICD implantation he underwent successful ablation of the triggering...

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Detalles Bibliográficos
Autores principales: Martin, Claire A., Nunn, Laurence, Lambiase, Pier D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527817/
https://www.ncbi.nlm.nih.gov/pubmed/29067911
http://dx.doi.org/10.1016/j.ipej.2017.05.006
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author Martin, Claire A.
Nunn, Laurence
Lambiase, Pier D.
author_facet Martin, Claire A.
Nunn, Laurence
Lambiase, Pier D.
author_sort Martin, Claire A.
collection PubMed
description A young man suffered cardiac arrests with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF) triggered by ventricular premature contractions (PVCs). The arrhythmia was resistant to anti-arrhythmics, so after ICD implantation he underwent successful ablation of the triggering VE beat, which was pace-mapped to the left posterior hemi-fascicle. We review the evidence for the role of the Purkinje network in the initiation and maintenance of PVT and VF, postulating a channelopathy as a possible underlying cause, and provide recommendations for PVC ablation.
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spelling pubmed-55278172017-08-01 Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation Martin, Claire A. Nunn, Laurence Lambiase, Pier D. Indian Pacing Electrophysiol J Case Report A young man suffered cardiac arrests with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF) triggered by ventricular premature contractions (PVCs). The arrhythmia was resistant to anti-arrhythmics, so after ICD implantation he underwent successful ablation of the triggering VE beat, which was pace-mapped to the left posterior hemi-fascicle. We review the evidence for the role of the Purkinje network in the initiation and maintenance of PVT and VF, postulating a channelopathy as a possible underlying cause, and provide recommendations for PVC ablation. Elsevier 2017-05-26 /pmc/articles/PMC5527817/ /pubmed/29067911 http://dx.doi.org/10.1016/j.ipej.2017.05.006 Text en © 2017, Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Martin, Claire A.
Nunn, Laurence
Lambiase, Pier D.
Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
title Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
title_full Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
title_fullStr Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
title_full_unstemmed Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
title_short Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
title_sort syncope in a young man: role of purkinje fibres in idiopathic ventricular fibrillation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527817/
https://www.ncbi.nlm.nih.gov/pubmed/29067911
http://dx.doi.org/10.1016/j.ipej.2017.05.006
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AT lambiasepierd syncopeinayoungmanroleofpurkinjefibresinidiopathicventricularfibrillation

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