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MYC‐y mice: From tumour initiation to therapeutic targeting of endogenous MYC

MYC is one of the best‐studied oncogenes in terms of mouse models of malignancy. MYC overexpression has been targeted to several tissues using transgenic constructs, and more recently as mouse models have evolved, conditional systems have been developed to allow the regulation of MYC expression or a...

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Detalles Bibliográficos
Autores principales: Morton, Jennifer P., Sansom, Owen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528411/
https://www.ncbi.nlm.nih.gov/pubmed/23523308
http://dx.doi.org/10.1016/j.molonc.2013.02.015