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Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine

The potential benefit in using IL-2 in immunotherapy for cancer and autoimmunity has been linked to the modulation of immune responses, which partly relies on a direct effect on Tregs populations. Here, we revisited the role of IL-2 in HIV infection and investigated whether its use as an adjuvant wi...

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Detalles Bibliográficos
Autores principales:	Brezar, Vedran, Hani, Lylia, Surenaud, Mathieu, Hubert, Audrey, Lacabaratz, Christine, Lelièvre, Jean-Daniel, Levy, Yves, Seddiki, Nabila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529021/ https://www.ncbi.nlm.nih.gov/pubmed/28708863 http://dx.doi.org/10.1371/journal.ppat.1006489

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