α-lipoic acid suppresses neuronal excitability and attenuates colonic hypersensitivity to colorectal distention in diabetic rats

AIM: Patients with long-standing diabetes often demonstrate intestinal dysfunction, characterized as constipation or colonic hypersensitivity. Our previous studies have demonstrated the roles of voltage-gated sodium channels NaV1.7 and NaV1.8 in dorsal root ganglion (DRG) in colonic hypersensitivity...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Yang, Pan-Pan, Song, Zhen-Yuan, Feng, Yu, Hu, Duan-Min, Hu, Ji, Xu, Guang-Yin, Zhang, Hong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529097/
https://www.ncbi.nlm.nih.gov/pubmed/28769585
http://dx.doi.org/10.2147/JPR.S135017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529097/
https://www.ncbi.nlm.nih.gov/pubmed/28769585
http://dx.doi.org/10.2147/JPR.S135017

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