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Natural Conformational Sampling of Human TNFα Visualized by Double Electron-Electron Resonance
Double electron-electron resonance in conjunction with site-directed spin labeling has been used to probe natural conformational sampling of the human tumor necrosis factor α trimer. We suggest a previously unreported, predeoligomerization conformation of the trimer that has been shown to be sampled...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529296/ https://www.ncbi.nlm.nih.gov/pubmed/28746848 http://dx.doi.org/10.1016/j.bpj.2017.06.007 |