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Natural Conformational Sampling of Human TNFα Visualized by Double Electron-Electron Resonance

Double electron-electron resonance in conjunction with site-directed spin labeling has been used to probe natural conformational sampling of the human tumor necrosis factor α trimer. We suggest a previously unreported, predeoligomerization conformation of the trimer that has been shown to be sampled...

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Detalles Bibliográficos
Autores principales:	Carrington, Bruce, Myers, William K., Horanyi, Peter, Calmiano, Mark, Lawson, Alastair D.G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2017
Materias:	Proteins
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529296/ https://www.ncbi.nlm.nih.gov/pubmed/28746848 http://dx.doi.org/10.1016/j.bpj.2017.06.007

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