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Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum

The mechanisms governing neutrophil response to Mycobacterium tuberculosis remain poorly understood. In this study we utilise biotagging, a novel genome-wide profiling approach based on cell type-specific in vivo biotinylation in zebrafish to analyse the initial response of neutrophils to Mycobacter...

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Detalles Bibliográficos
Autores principales: Kenyon, Amy, Gavriouchkina, Daria, Zorman, Jernej, Napolitani, Giorgio, Cerundolo, Vincenzo, Sauka-Spengler, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529371/
https://www.ncbi.nlm.nih.gov/pubmed/28747644
http://dx.doi.org/10.1038/s41598-017-06099-x