Establishment and Characterization of a Novel Rat Model of Mechanical Low Back Pain Using Behavioral, Pharmacologic and Histologic Methods

Chronic low back pain (LBP), the leading cause of disability globally, is notoriously difficult to treat. Most rodent models of LBP mimic lumbar radicular pain rather than mechanical LBP. Here, we describe establishment of a new rat model of mechanical LBP that is devoid of a neuropathic component....

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Detalles Bibliográficos
Autores principales: Muralidharan, Arjun, Park, Thomas S. W., Mackie, John T., Gimenez, Luiz G. S., Kuo, Andy, Nicholson, Janet R., Corradini, Laura, Smith, Maree T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529395/
https://www.ncbi.nlm.nih.gov/pubmed/28798688
http://dx.doi.org/10.3389/fphar.2017.00493

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