Mutations targeting the coagulation pathway are enriched in brain metastases

Brain metastases (BMs) are the most common malignancy of the central nervous system. Recently it has been demonstrated that plasminogen activator inhibitor serpins promote brain metastatic colonization, suggesting that mutations in serpins or other members of the coagulation cascade can provide crit...

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Detalles Bibliográficos
Autores principales: Richichi, Cristina, Fornasari, Lorenzo, Melloni, Giorgio E. M., Brescia, Paola, Patanè, Monica, Del Bene, Massimiliano, Mustafa, Dana A. M., Kros, Johan M., Pollo, Bianca, Pruneri, Giancarlo, Sciandivasci, Angela, Munzone, Elisabetta, DiMeco, Francesco, Pelicci, Pier Giuseppe, Riva, Laura, Pelicci, Giuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529435/
https://www.ncbi.nlm.nih.gov/pubmed/28747664
http://dx.doi.org/10.1038/s41598-017-06811-x

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