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4-dimensional functional profiling in the convulsant-treated larval zebrafish brain
Functional neuroimaging, using genetically-encoded Ca(2+) sensors in larval zebrafish, offers a powerful combination of high spatiotemporal resolution and higher vertebrate relevance for quantitative neuropharmacological profiling. Here we use zebrafish larvae with pan-neuronal expression of GCaMP6s...
Autores principales: | Winter, Matthew J., Windell, Dylan, Metz, Jeremy, Matthews, Peter, Pinion, Joe, Brown, Jonathan T., Hetheridge, Malcolm J., Ball, Jonathan S., Owen, Stewart F., Redfern, Will S., Moger, Julian, Randall, Andrew D., Tyler, Charles R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529444/ https://www.ncbi.nlm.nih.gov/pubmed/28747660 http://dx.doi.org/10.1038/s41598-017-06646-6 |
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