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Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2

Tumor necrosis factor receptor 2 (TNFR2) is known to mediate immune suppression and tissue regeneration. Interestingly, the transmembrane form of tumor necrosis factor (tmTNF) is necessary to robustly activate TNFR2. To characterize the stoichiometry and composition of tmTNF during TNFR2 activation,...

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Detalles Bibliográficos
Autores principales:	Fischer, Roman, Marsal, Jessica, Guttà, Cristiano, Eisler, Stephan A., Peters, Nathalie, Bethea, John R., Pfizenmaier, Klaus, Kontermann, Roland E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529482/ https://www.ncbi.nlm.nih.gov/pubmed/28747780 http://dx.doi.org/10.1038/s41598-017-06993-4

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