Downregulation of Interferon-β and Inhibition of TLR3 Expression are associated with Fatal Outcome of Severe Fever with Thrombocytopenia Syndrome

Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease with high mortality and increasing prevalence in the East Asia. Though the etiological agent has been identified as a novel Bunyavirus, cellular mechanisms of viral pathogenesis and host immune response to SFTS viru...

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Detalles Bibliográficos
Autores principales: Song, Peixin, Zheng, Nan, Zhang, Li, Liu, Yong, Chen, Taoyu, Bao, Changjun, Li, Zhifeng, Yong, Wei, Zhang, Yongyang, Wu, Chao, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529500/
https://www.ncbi.nlm.nih.gov/pubmed/28747721
http://dx.doi.org/10.1038/s41598-017-06921-6

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