AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination

A defining hallmark of primary and metastatic cancers is the migration and invasion of malignant cells. These invasive properties involve altered dynamics of the cytoskeleton and one of its major structural components β-actin. Here we identify AIM1 (absent in melanoma 1) as an actin-binding protein...

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Detalles Bibliográficos
Autores principales: Haffner, Michael C., Esopi, David M., Chaux, Alcides, Gürel, Meltem, Ghosh, Susmita, Vaghasia, Ajay M., Tsai, Harrison, Kim, Kunhwa, Castagna, Nicole, Lam, Hong, Hicks, Jessica, Wyhs, Nicolas, Biswal Shinohara, Debika, Hurley, Paula J., Simons, Brian W., Schaeffer, Edward M., Lotan, Tamara L., Isaacs, William B., Netto, George J., De Marzo, Angelo M., Nelson, William G., An, Steven S., Yegnasubramanian, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529512/
https://www.ncbi.nlm.nih.gov/pubmed/28747635
http://dx.doi.org/10.1038/s41467-017-00084-8

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