The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways

Long noncoding RNAs (lncRNAs) play important roles in various biological processes such as proliferation, cell death and differentiation. Here, we show that a liver-enriched lncRNA, named liver fibrosis-associated lncRNA1 (lnc-LFAR1), promotes liver fibrosis. We demonstrate that lnc-LFAR1 silencing...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Han, Xiaohui, Zhang, Zhen, Zheng, Lina, Hu, Zhimei, Yao, Qingbin, Cui, Hongmei, Shu, Guiming, Si, Maojie, Li, Chan, Shi, Zhemin, Chen, Ting, Han, Yawei, Chang, Yanan, Yao, Zhi, Han, Tao, Hong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529527/
https://www.ncbi.nlm.nih.gov/pubmed/28747678
http://dx.doi.org/10.1038/s41467-017-00204-4

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