Metabolite Profiling, Pharmacokinetics, and In Vitro Glucuronidation of Icaritin in Rats by Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry

Icaritin is a naturally bioactive flavonoid with several significant effects. This study aimed to clarify the metabolite profiling, pharmacokinetics, and glucuronidation of icaritin in rats. An ultra-performance liquid chromatography coupled with mass spectrometry (UPLC-MS) assay was developed and v...

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Detalles Bibliográficos
Autores principales: Zhang, Beibei, Chen, Xiaoli, Zhang, Rui, Zheng, Fangfang, Du, Shuzhang, Zhang, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529662/
https://www.ncbi.nlm.nih.gov/pubmed/28785509
http://dx.doi.org/10.1155/2017/1073607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529662/
https://www.ncbi.nlm.nih.gov/pubmed/28785509
http://dx.doi.org/10.1155/2017/1073607

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