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Metabolite Profiling, Pharmacokinetics, and In Vitro Glucuronidation of Icaritin in Rats by Ultra-Performance Liquid Chromatography Coupled with Mass Spectrometry
Icaritin is a naturally bioactive flavonoid with several significant effects. This study aimed to clarify the metabolite profiling, pharmacokinetics, and glucuronidation of icaritin in rats. An ultra-performance liquid chromatography coupled with mass spectrometry (UPLC-MS) assay was developed and v...
Autores principales: | Zhang, Beibei, Chen, Xiaoli, Zhang, Rui, Zheng, Fangfang, Du, Shuzhang, Zhang, Xiaojian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529662/ https://www.ncbi.nlm.nih.gov/pubmed/28785509 http://dx.doi.org/10.1155/2017/1073607 |
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