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Effects of 17-allylamino-17-demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT-116 cells

The present study investigated the effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on apoptosis and the cell cycle of the HCT-116 human colon carcinoma cell line, with the aim of elucidating their underlying mechanisms. MTT was used to examine the inhibitory effects of 17-...

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Detalles Bibliográficos
Autores principales:	Zhao, Xuerong, Wang, Jianping, Xiao, Lijun, Xu, Qian, Zhao, Enhong, Zheng, Xin, Zheng, Huachuan, Zhao, Shuang, Ding, Shi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530076/ https://www.ncbi.nlm.nih.gov/pubmed/28789442 http://dx.doi.org/10.3892/ol.2017.6442

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