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Altered expression of cellular proliferation, apoptosis and the cell cycle-related genes in lung cancer cells with acquired resistance to EGFR tyrosine kinase inhibitors

Non-small cell lung cancers harboring somatic gain-of-function mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain respond well to treatment with EGFR tyrosine kinase inhibitors (TKIs) including gefitinib and erlotinib. However, all patients who experience a marked improv...

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Detalles Bibliográficos
Autores principales:	Lee, Tae-Gul, Jeong, Eun-Hui, Min, Il Jae, Kim, Seo Yun, Kim, Hye-Ryoun, Kim, Cheol Hyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530116/ https://www.ncbi.nlm.nih.gov/pubmed/28781659 http://dx.doi.org/10.3892/ol.2017.6428

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