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Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype
The present report describes a unique infantile acute lymphoblastic leukemia (ALL) case with cryptic mixed-lineage leukemia (MLL) rearrangements with 11q23 chromosomal translocation. MLL break-apart signals were identified by fluorescence in situ hybridization, and transcriptome sequencing revealed...
Autores principales: | Hiwatari, Mitsuteru, Seki, Masafumi, Akahoshi, Shogo, Yoshida, Kenichi, Miyano, Satoru, Shiraishi, Yuichi, Tanaka, Hiroko, Chiba, Kenichi, Ogawa, Seishi, Takita, Junko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530220/ https://www.ncbi.nlm.nih.gov/pubmed/28781666 http://dx.doi.org/10.3892/ol.2017.6430 |
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