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Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases

OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases, comprising seven categories. Genetic data could potentially be used to help redefine JIA categories and improve the current classification system. The human leucocyte antigen (HLA) region is strongly associated wit...

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Detalles Bibliográficos
Autores principales:	Hinks, A, Bowes, J, Cobb, J, Ainsworth, H C, Marion, M C, Comeau, M E, Sudman, M, Han, B, Becker, M L, Bohnsack, J F, de Bakker, P I W, Haas, J P, Hazen, M, Lovell, D J, Nigrovic, P A, Nordal, E, Punnaro, M, Rosenberg, A M, Rygg, M, Smith, S L, Wise, C A, Videm, V, Wedderburn, L R, Yarwood, A, Yeung, R S M, Prahalad, S, Langefeld, C D, Raychaudhuri, S, Thompson, S D, Thomson, W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2017
Materias:	Basic and Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530326/ https://www.ncbi.nlm.nih.gov/pubmed/27998952 http://dx.doi.org/10.1136/annrheumdis-2016-210025

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