Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

OBJECTIVE: Transcribed-ultraconserved regions (T-UCR) are long non-coding RNAs which are conserved across species and are involved in carcinogenesis. We studied T-UCRs downstream of the Wnt/β-catenin pathway in liver cancer. DESIGN: Hypomorphic Apc mice (Apcfl/fl) and thiocetamide (TAA)-treated rats...

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Detalles Bibliográficos
Autores principales: Carotenuto, Pietro, Fassan, Matteo, Pandolfo, Rosantony, Lampis, Andrea, Vicentini, Caterina, Cascione, Luciano, Paulus-Hock, Viola, Boulter, Luke, Guest, Rachel, Quagliata, Luca, Hahne, Jens Claus, Ridgway, Rachel, Jamieson, Tam, Athineos, Dimitris, Veronese, Angelo, Visone, Rosa, Murgia, Claudio, Ferrari, Giulia, Guzzardo, Vincenza, Evans, Thomas Ronald Jeffry, MacLeod, Martin, Feng, Gui Ji, Dale, Trevor, Negrini, Massimo, Forbes, Stuart J, Terracciano, Luigi, Scarpa, Aldo, Patel, Tushar, Valeri, Nicola, Workman, Paul, Sansom, Owen, Braconi, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
GI cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530482/
https://www.ncbi.nlm.nih.gov/pubmed/27618837
http://dx.doi.org/10.1136/gutjnl-2016-312278

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